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1.
Pakistan Journal of Medical Sciences. 2017; 33 (1): 3-7
in English | IMEMR | ID: emr-185467

ABSTRACT

Objective: To determine the visual outcome in patients with acute Central serous chorioretinopathy [CSCR] and to analyze the association of clinical, angiographic and tomographic factors with final visual outcome in Pakistani population


Methods: This study was conducted at AFIO Rawalpindi and PNS Shifa Naval hospital Karachi from November 2011 to August 2016. Fifty five eyes of 53 patients with acute CSCR were included. All patients underwent a detailed ophthalmic examination including SD OCT imaging at baseline, One month and three month and FFA was performed at baseline. Primary outcome measures were measurement of initial and final BCVA and CFT. SPSS 13.0 was used for the analysis of data


Results: Mean age of study population was 36.66 +/- 6.24 years. On OCT mean CFT at baseline was 467.49 +/- 144.80 microm in affected eye, whereas mean CFT measurements at final follow up was 244.67 +/- 32.99 microm [p <0.01]. Presenting mean log MAR BCVA was 0.47 +/- 0.25 and final mean log MAR BCVA was 0.18 +/- 0.14 [p <0.01]. Baseline BCVA showed statistically significant association with final BCVA [p=0.03]


Conclusion: Presenting VA of 6/12 or better is associated with favorable visual outcome in patients with acute CSCR

3.
PAFMJ-Pakistan Armed Forces Medical Journal. 2017; 67 (1): 47-50
in English | IMEMR | ID: emr-186429

ABSTRACT

Objective: To determine the frequency of vitreo macular traction [VMT] in patients of diabetic macular edema [DME] as detected on spectral domain optical coherence tomography [SD-OCT]


Study Design: Cross-sectional study


Place and Duration of Study: Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi, from May 2013 to Jan 2014. Patients and Methods: Diabetic patients of less than 18 years of age with DME and central macular thickness of more than 250 micrometers [micro m] were included. The patients with idiopathic VMT, history of vitreoretinal surgery, and history of other retinal vascular diseases were excluded from the study. Dilated fundus was done in each patient using 90 D lens on a slit lamp biomicroscope and patients with diabetic retinopathy changes and DME were subjected to OCT examination using Topcon 3-D OCT 1000 [Topcon Corporation]. Record of each patient including demographic data, ocular findings and OCT data were endorsed on a pre-devised proforma


Results: Seventy one eyes of 68 patients were included, 36 [50.7%] were males and 35 [49.29%] were females. Mean age was 53.17 +/- 8.79 years. Mean central macular thickness [CMT] was 361.8 +/- 109 micro m. VMT was detected in 17 [23.9%] eyes. Amongst these, 2[12.5%] eyes had vitreofoveal traction, epiretinal membrane was found in 4 [25%] eyes and 11[62.5%] eyes had extra foveal VMT


Conclusion: Detection of VMT in about a quarter of cases reflects that OCT is a viable tool for early detection of vitreomacular interface abnormalities

4.
PAFMJ-Pakistan Armed Forces Medical Journal. 2017; 67 (2): 238-242
in English | IMEMR | ID: emr-186810

ABSTRACT

Objective: To determine the relationship between mean axial length and mean peripapillary retinal nerve fibre layer [RNFL] thickness using spectral domain optical coherence tomography [SD OCT] in healthy subjects


Study Design: Cross sectional study


Place and Duration of Study: Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi, from Dec 2014 to Aug 2015


Material and Methods: Data of 300 eyes of 300 healthy volunteers were collected at AFIO from December 2014 to August 2015 and analysed. Axial length and RNFL thickness of each volunteer was calculated using laser interferometer [IOL master] and SD OCT respectively. Eyes were divided in three groups based on axial length. Statistical analysis of the data were done using SPSS version 17.0


Results: Mean age of study population was 23.16 +/- 3.73 years. Mean axial length was 24.40 +/- 1.50 millimetres [mm]. Mean of average peripapillary RNFL thickness was 128.87 +/- 9.94 micrometres [micro m]. Mean peripapillary RNFL thickness of superior, inferior, nasal and temporal quadrant was 158.27 +/- 11.04 micro m, 152.92 +/- 14.54 micro m, 103.85 +/- 5.01 micro m and 100.45 +/- 11.59 micro m respectively. Mean RNFL thickness, as well as RNFL thicknesses of each quadrant was also significantly different between hypermetropic, emmetropic and myopic eyes [p-value<0.001]. There was also a strong negative correlation between axial length and peripapillary retinal nerve fibre layer thickness [r= -0.964, p-value<0.001]


Conclusion: Variation in axial length significantly affects the measurement of RNFL thickness and must be counted for, while diagnosing glaucoma on basis of thinning of RNFL

5.
Pakistan Journal of Medical Sciences. 2017; 33 (2): 471-475
in English | IMEMR | ID: emr-187920

ABSTRACT

Objective: To evaluate the efficacy and safety of Optic Nerve Sheath Fenestration [ONSF] in patients with raised intracranial pressure [ICP]


Methods: This Quasi Experimental Study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi from July 2013 to July 2015.Thirty one eyes of 18 patients who underwent ONSF for raised ICP were followed up for one year to ascertain efficacy and safety of ONSF procedure


Results: Thirteen [72.22%] patients underwent ONSF bilaterally, while five [27.78%] underwent unilateral ONSF. Best corrected visual acuity [BCVA] improved in 24 [77.4%], remained stable in four [12.9%] and deteriorated in three [9.7%] patients. Papilledema improved in 27 [87.1%] while remained stable in four [12.9%] according to Frisenscale of Papilledema. Change in BCVA and papilledema from pre-operative values was statistically significant [p<0.001]. There was significant negative correlation [r= -0.434, p=.017] between duration of symptoms before presentation and improvement in BCVA. Common complications were a tonic pupil, subconjunctival haemorrhage, chemosis, weakness of recti and diplopia


Conclusion: ONSF is an effective procedure with statistically significant improvement in BCVA and reduction in severity of papilledema

6.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2017; 27 (5): 288-291
in English | IMEMR | ID: emr-187988

ABSTRACT

Objective: To compare the clinical profile, systemic risk factors, and characteristics of rhegmatogenous retinal detachment [RRD] in pseudophakic and phakic eyes


Study Design: Cross-sectional comparative study


Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi from August 2013 to August 2015


Methodology: A total of 164 eyes [96 pseudophakic patients and 68 phakic patients] with RRD were analyzed. Demographic data and associated known risk factors of study population were acquired. Retinal examination was done by single experienced retinal surgeon using indirect ophthalmoscopy for type of retinal break, location and number of retinal breaks, status of macula, morphological extent of RRD and retinal degenerations. All the findings were endorsed on a pre-devised proforma


Results: Mean age of patients in pseudophakic and phakic groups was 61.18 +/- 10.39 and 59.27 +/- 9.57 years, respectively. Frequency of male patients in pseudophakic and phakic groups was 74% and 57.4%, respectively. Mean axial length in pseudophakic and phakic groups was 23.13 +/- 2.18 mm and 21.9 +/- 2.01 mm, respectively. Difference in axial length and gender distribution between two groups was statistically significant [p < 0.05]. Difference in frequency of patients with history of hypertension and myopia between two groups was statistically significant [p < 0.05]. Characteristics of RRD [type, location and number of retinal breaks, macula status, and extent of RRD] between groups were not statistically significant


Conclusion: RRD is more common in pseudophakic patients with male gender, increased axial length, myopia, and hypertension

7.
Pakistan Journal of Medical Sciences. 2017; 33 (6): 1307-1311
in English | IMEMR | ID: emr-189377

ABSTRACT

Objective: To compare corneal morphological parameters between diabetics and age matched non-diabetic control subjects and to evaluate the correlation of these parameters in relation to duration of diabetes mellitus [DM], glycemic status and severity of diabetic retinopathy.[DR]


Methods: This cross sectional comparative study was conducted at the Department of Ophthalmology, PNS Shifa Karachi from February 2016 to January 2017. Patients with ages between 10 to 80 years of either gender who were diagnosed to have DM were recruited in the study. Control group comprised of age matched healthy volunteers who did not have DM. Corneal morphological parameters [CED, Average cell size, CV of cell size and hexagonality] was evaluated in each subject with non-contact specular microscope and findings were endorsed on a pre devised proforma


Results: Data of 298 eyes [149 diabetic patients and 149 healthy controls] was evaluated. Mean corneal endothelial cell density [CED] of diabetic population was 2494.47 +/- 394.10 cells/mm[2], while mean CED of control group was 2574.46 +/- 279.97 cells/mm[2] [p = 0.04]. Between group differences in mean average cell size, CV of cell size and hexagonality was statistically not significant. Analysis of corneal endothelial parameters among subgroups of patients with no DR, with NPDR and PDR did not show statistically significant difference. Moreover, patients with diabetes of more than 10 years duration had significantly lower CED [p <0.01] and larger average cell size [p= 0.03]. Duration of DM was significantly correlated with type of DR, HbA1c level, CED, polymegethism and hexagonality


Conclusion: Mean corneal endothelial cell density [CED] was found to be significantly lower in diabetic population as compared to healthy controls

8.
PAFMJ-Pakistan Armed Forces Medical Journal. 2017; 67 (3): 391-396
in English | IMEMR | ID: emr-188566

ABSTRACT

Objective: To compare the mean changes in central corneal thickness [CCT] and corneal endothelial-cell density [CED] after removal of silicon oil [ROSO] using anterior [limbal] versus posterior [pars plana] approach in aphakic patients following successful retinal re attachment surgery


Study Design: Randomized controlled trial


Place and Duration of Study: Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi, from Dec 2014 to Aug 2015


Material and Methods: Sixty eyes of 60 aphakic patients who underwent removal of silicon oil from December 2014 to August 2015 in AFIO after successful retinal re-attachment surgery were analysed. Thirty eyes underwent removal of silicon oil through anterior [limbal] approach [groupl] and 30 eyes through posterior [pars plana] approach [group-2]. Pre-operative central corneal thickness and corneal endothelial-cell density was measured and compared with central corneal thickness and corneal endothelial-cell density measurements 3 months after removal of silicon oil


Results: Mean age of study population was 49.93 +/- 5.18 years. Both groups were age and sex matched [p=0.694 and p=0.80 respectively]. In group 1, mean change in CCT was 1.80 +/- 6.58 micro meters [jum] and mean change in CED was 196.30 +/- 33.78 cells per millimetres square [mm[2]], while in group 2, mean change in CCT was 1.63 +/- 8.96 microm and mean change in CED was 60.20 +/- 39.75 cells/mm2 after 3 months of ROSO. Mean change in CCT between two groups was not statistically significant [p=0.935], however, mean change in CED between two groups was statistically significant [p<0.001]


Conclusion: Removal of silicon oil through anterior [limbal] approach causes significant reduction in CED, as compared to posterior [pars plana] approach in aphakic patients following successful retinal re attachment surgery


Subject(s)
Humans , Female , Male , Adult , Middle Aged , Aged , Endothelium, Corneal , Corneal Pachymetry , Aphakia , Retinal Detachment/surgery , Randomized Controlled Trials as Topic
9.
PAFMJ-Pakistan Armed Forces Medical Journal. 2016; 66 (1): 47-52
in English | IMEMR | ID: emr-178737

ABSTRACT

Objective: To analyze the demography, characteristics, visual and anatomical outcomes of combat ocular injuries sustained by Pakistani troops


Study Design: Case series


Place and Duration of Study: Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi, from January 2010 to June 2014


Material and Methods: Data of 156 eyes of 120 war wounded patients treated at AFIO from 2010 - 2014 was retrieved and analysed. Record of each patient was evaluated and demographic data, mode and type of injury, initial and final visual acuity [VA], associated globe injuries, concomitant non-ocular injuries, type of surgical procedures and complications were endorsed on a pre-devised proforma. Injuries were classified according to the Birmingham Eye Trauma Terminology [BETT]. Statistical analysis of the data was done using SPSS version 13.0


Results: Mean age of study population was 28.33 +/- 7.70 years. Improvised explosive device [IED] blast was the most common mode injury occurring in 51 [42.5%] of casualties. Forty eight [30.76%] eyes sustained closed globe injuries while 108 [69.23%] eyes had open globe injuries. Thirty one [19.87%] eyes were initially managed conservatively, while primary corneo scleral repairs were done in 77 [49.35%] eyes. Overall, final visual outcome was significantly better in closed globe injuries as compared to open globe injuries with 26 [54.16%] eyes with closed globe injury achieving final VA of >/= 6/12 as compared to 10 [9.25%] eyes with open globe injuries


Conclusion: Closed globe combat ocular injuries have better visual outcome as compared to open globe injuries

10.
PAFMJ-Pakistan Armed Forces Medical Journal. 2016; 66 (1): 169-170
in English | IMEMR | ID: emr-178762

ABSTRACT

As the paintball sports including war games have become popular, the incidence of paintball ocular injuries has increased considerably. These injuries are usually blunt trauma resulting from paintball projectiles, which travel at a speed of 80-130 m/s. We report 3 cases of ocular paintball injuries with compromised visual outcome sustained in unprotected environment highlighting the importance of compulsory use of American society for testing and material [ASTM] compliant eye protective devices [EPD] during paintball related activities

11.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2016; 26 (8): 692-695
in English | IMEMR | ID: emr-183673

ABSTRACT

Objective: to determine the frequency of various systemic risk factors associated with acute central serous chorioretinopathy [CSCR] in our setup


Study Design: descriptive case series


Place and Duration of Study: armed Forces Institute of Ophthalmology [AFIO], Rawalpindi, from July 2011 to June 2014


Methodology: all consecutive patients with acute CSCR who presented in the outpatient department during the study period were recruited. Clinical findings were endorsed on a pre-devised proforma with special emphasis on inquiring about known systemic risk factors for CSCR in detail from each patient. Patients were managed conservatively with control of modifiable risk factors and topical 0.1% Nepafenac eye drops. Analysis of data was done using SPSS version 13.0


Results: forty-four eyes of 42 patients were eligible for final analysis. The mean age of study population was 37.38 +/-6.31 years with 38 [90.47%] male patients. Elevated serum cortisol and serum testosterone levels were found in 3 and 2 patients, respectively. Known systemic risk factors for CSCR were present in 36 [85.71%] patients with emotional stress/psychiatric disorder 15 [35.71%], Type A personality 11 [26.19%], smoking 10 [19.04%], hypertension 5 [11.90%], and acid peptic disease 4 [9.52%] were the most frequently found risk factors


Conclusion: emotional stress/psychiatric illness, hypertension, acid peptic disease and use of exogenous steroids and other medicines are the established risk factors for CSCR that can be modified / withdrawn to reduce the morbidity related to CSCR

12.
Pakistan Journal of Medical Sciences. 2016; 32 (6): 1349-1353
in English | IMEMR | ID: emr-184955

ABSTRACT

Objective: To compare serum cholesterol, TG, HDL-C and LDL-C concentrations between type-2 Diabetes mellitus [DM] patients with retinopathy and without retinopathy and to study association between various modifiable risk factors of Diabetic retinopathy [DR]


Methods: The study included 300 patients with type 2 DM; 140 of them were without DR [Group-I] and 160 were with DR [Group-II]. Serum total cholesterol, LDL-C, HDL-C, and TG levels were determined. SPSS 17.0 for windows was used for statistical analysis


Results: Overall, mean age of study population was 48.86 +/- 5.62 years. Subjects with DR were older [P < 0.018], had higher fasting plasma glucose [P < 0.01] and higher HbA1c [P <0.01] concentrations compared with those without DR. Analysis of serum cholesterol, LDL-C, HDL-C and TG among subgroups of patients with no DR, with NPDR and PDR showed statistically significant difference [p <0.01]. There was strong positive correlation of severity of DR with BSF, HbA1c, serum LDL-C, total cholesterol and TG


Conclusion: The serum cholesterol, TG, HDL-C and LDL-C concentrations were found to be significantly deranged in patients with DR as compared to those without DR

13.
Pakistan Journal of Medical Sciences. 2016; 32 (6): 1533-1536
in English | IMEMR | ID: emr-184990

ABSTRACT

Objective: To compare mean retinal nerve fiber layer [RNFL] thickness in patients having pseudo exfoliation [PXF] with normal age matched controls using spectral domain optical coherence tomography [SD-OCT]


Methods: This was a case control study conducted at Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi from 12 June 2013 to 12 January 2014. Seventy eyes [Group A - 35 patients with PXF and Group B - 35 healthy age matched subjects] of more than 40 years of age were included in the study. Intraocular pressure [IOP] was measured with Goldmann applanation tonometer [GAT] and peripapillary RNFL thickness was measured in four quadrants with SD-OCT [Topcon 3D OCT-1000 Mark II] in all subjects. Data was analyzed using the SPSS version 14


Results: Mean age of group A [PXF patients] was 65.63 +/- 8.47 years and of group B [Healthy subjects] was 64.31 +/- 6.51 years [p = 0.470]. Both groups were gender matched with male preponderance [p = 0.673]. Mean IOP in each group was 13.80 +/- 2.59 mm Hg, and 13.49 +/- 2.07 mm Hg respectively [p= 0.578]. Mean average peripapillary RNFL thickness was 77.46 +/- 12.17 micro m in group A and 83.96 +/- 10.58 micro m in group B. Statistically significant differences were detected between two groups for mean average RNFL thickness [p= 0.020] and mean RNFL thickness in inferior quadrant [p=0.014]


Conclusion: PXF patients with normal IOP and visual fields have thin RNFL as compared to healthy age matched controls. Therefore routine assessment and follow up of PXF patients with OCT may help in early diagnosis of PXF glaucoma

14.
PAFMJ-Pakistan Armed Forces Medical Journal. 2015; 65 (6): 817-820
in English | IMEMR | ID: emr-173367

ABSTRACT

Objective: To compare the mean retinal nerve fiber layer [RNFL] thickness in Primary open angle glaucoma [POAG] patients and healthy age matched adults


Study Design: Case control study


Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi from 12[th] December 2011 to 17[th] October 2012


Material and Methods: Sixty subjects were included in the study, 30 cases and 30 controls, by non-probability consecutive sampling. In group A, patients of POAG were included and in group B, healthy adults having normal intraocular pressure were included. Mean retinal nerve fiber layer thickness [RNFL] measurements and mean of three intraocular pressure [IOP] readings of 30 patients of POAG were taken. RNFL thickness was obtained by spectral domain optical coherence tomography. IOP readings were taken with calibrated Goldman applanation tonometer


Results: Mean RNFL thickness of 66.19 +/- 14.83 microns in group A eyes was significantly lower than mean RNFL thickness of 96.46 +/- 14.76 microns in normal adults [p<0.001]


Conclusion: The overall thinner mean retinal nerve fiber layer thickness in POAG patients as compared with normal age matched individuals highlights the importance of early diagnosis and prompt intervention in such patients to reduce the morbidity related to potentially blinding but treatable disease like glaucoma

15.
PAFMJ-Pakistan Armed Forces Medical Journal. 2015; 65 (2): 231-234
in English | IMEMR | ID: emr-168254

ABSTRACT

To evaluate the efficacy of primary and redo retinectomy in eyes with complex retinal detachment. Quasi-experimental study. Armed Forces Institute of Ophthalmology Rawalpindi from Jan 2012 to June 2013. Fifty eight eyes [patients] underwent relaxing retinectomies for complex retinal detachment with proliferative vitreoretinopathy or intrinsic retinal shortening. Operative technique included pars plana vitrectomy, proliferative vitreoretinopathy management, use of intraoperative perfluorocarbon liquid, retinectomy, endolaser and intraocular temponade. The main outcome was anatomic success, defined as complete retinal reattachment at four months follow up. Eighteen eyes out of the same primary group underwent second retinectomy because of anatomical failure. Mean age of study population was 53.78 +/- 15.11 years, 56.9% of patients were male[s]. Anatomic success rate after 1[st] retinectomy was achieved in 68.96% [40 eyes out of 58]. In eighteen eyes that underwent 2[nd] retinectomy, anatomic success rate was 72.22% [13 eyes out of 18]. Overall success rate was 91.3% [53 eyes out of 58] in our study. Relaxing retinectomies for retinal shortening can improve the anatomical success rate in patients with complex RD


Subject(s)
Humans , Male , Female , Retinal Detachment , Vitreoretinopathy, Proliferative , Vitrectomy
16.
PAFMJ-Pakistan Armed Forces Medical Journal. 2015; 65 (1): 94-98
in English | IMEMR | ID: emr-168291

ABSTRACT

To compare the intraocular pressure [IOP] lowering effect of topical drug combination [Latanoprost and Timolol] with Latanoprost alone in patients of Primary Open Angle Glaucoma [POAG]. Randomized controlled Trials [RCT]. Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi from December 2009 to May 2011. A total of 240 eyes of 120 patients [68 males and 52 females] were included in the study. The patients were randomized into two groups of 60 each using random numbers table. Group A [60 patients, 12Q eyes] were put on topical drug combination of Latanoprost and Timolol eye drops and Group B [60 patients, 120 eyes] were treated with topical Latanoprost eye drops alone. IOP assessments were done at baseline, 2 weeks, 4 weeks and 8 weeks intervals after initiation of treatment. Both the groups were age matched with mean age in Group A was 56.39 +/- 8.50 years and in Group B was 55.61 +/- 8.95 years [p=0.09]. Both groups showed significant IOP decrease from the baseline at each follow up interval. However after 8 weeks of start of treatment, pressure lowering effect in group A [14.73 +/- 2.50 mmHg] was significantly more as compared to Group B [9.10 +/- 2.51 mmHg] [p<0.001]. Combination therapy of Latanoprost and Timolol is more effective as compared to monoyherapy with Latanoprost in lowering IOP of patients with POAG


Subject(s)
Humans , Male , Female , Prostaglandins F, Synthetic , Timolol , Glaucoma, Open-Angle
17.
PAFMJ-Pakistan Armed Forces Medical Journal. 2015; 65 (1): 105-109
in English | IMEMR | ID: emr-168293

ABSTRACT

To compare the effect of rapid and conventional methods of corneal collagen cross linking [CXL] on visual acuity [VA] and corneal parameters in Keratoconus. Randomized control trial. Armed Forces Institute of Ophthalmology, Feb 2012 to Apr 2013. Thirty patients, fifteen in each group, were randomized by non probability consecutive sampling to rapid or conventional CXL group. Pre and post operative [6 months] best corrected visual acuity [BCVA], anterior and posterior keratometric [K] values and pachymetry were recorded. Intra and inter group comparison of all these parameters were statistically analyzed. All thrty patients showed either stabilization or improvement in BCVA. Both groups showed comparable results in terms of improvement BCVA [p = 0.682], reduction in the corneal thickness at thinnest point [p = 0.062], anterior flat and steep K [p = 0.633, p = 0.443 respectively] and posterior flat and steep K values [p = 0.130, p = 0.068] at six months duration. Conventional and rapid methods of CXL are comparable in terms of their effect on VA and corneal parameters


Subject(s)
Humans , Male , Female , Cornea , Collagen , Visual Acuity
18.
PAFMJ-Pakistan Armed Forces Medical Journal. 2015; 65 (4): 502-505
in English | IMEMR | ID: emr-166626

ABSTRACT

To compare the efficacy of injection of extralesional subcutaneous triamcinolone and intralesional triamcinolone in the treatment of primary chalazion. Randomized controlled trial. Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi, from 1[st] September 2011 to 31[st] March 2012. Ninety two patients fulfilling the selection criteria were randomly divided into two groups of 46 patients each group A intralesional triamcinolone [IT] patients received a single extralesional subcutaneous triamcinolone injection while group B extralesional triamcinolone [ET] patients received intralesional triamcinolone injection. Main outcome measure was reduction in chalazion size to 2mm or smaller after steroid injection at 4 weeks follow up visit. The size of chalazion was measured at baseline and then at 2 weeks and 4 weeks post steroid injections. Data analysis was done by "statistical package for social sciences [SPSS] version 13.0 for windows. Both the groups were age matched with mean age of 30.46 +/- 10.09 years in group A and 29.13 +/- 6.04 yrs in group B. Among the subjects, there were 64 male and 28 female patients. Out of 92 patients, resolution was seen in 84.8% [39 out of 46 cases] in ET group and 82.6% [38 out of 46 cases] in IT group at 4 weeks follow up that was not statistically significant [p = 0.45]. Injection of extralesional subcutaneous triamcinolone is as effective as intralesional triamcinolone in treatment of chalazion


Subject(s)
Humans , Adult , Female , Male , Triamcinolone , Injections, Subcutaneous , Injections, Intralesional
19.
PAFMJ-Pakistan Armed Forces Medical Journal. 2012; 62 (3): 409-412
in English | IMEMR | ID: emr-150282

ABSTRACT

To compare the intraocular pressure [IOP] lowering effect of Timolol/Dorzolamide combined preparation to that of Latanoprost in eyes with primary open angle glaucoma. Randomized control trial [RCT]. The Eye department, Military Hospital, Rawalpindi, over six months, from 9th June 2008 to 8th December 2008. Eighty Six patients included were divided into two equal groups. Initial IOP measurement was taken for every patient using Goldmann Applanation Tonometer with Fluorescein. Topical Antiglaucoma therapy was started in patients of either group. Group A patients were administered timolol/dorzolamide combined preparation where as latanoprost was administered to group B patients. Follow up IOP measurements were recorded at 4 week and 8 week interval for every patient and findings were endorsed on a pre-designed proforma. Data were analyzed using SPSS version 11.0. Eight week follow up IOP of Group A [14.51 +/- 2.54] was significantly lower than the initial IOP [19.37 +/- 2.49] [p<0.05]. For Group B, difference between initial IOP [19.53 +/- 2.69] and 8 week follow up IOP [14.09 +/- 2.23] was also statistically significant. The difference between mean IOP of the two groups at 4 week [p=0.284] and at 8 week [p=0.419] follow up was not statistically significant. Frequency of cases with >/= 4 mm Hg drop at 4 week follow up was 26 [60.46%] in group A as against 29 [67.44%] in group B [p=0.50], whereas at 8 week follow up it was 31 [72.09%] for group A and 34 [79.07%] in group B [p=0.451]. The results suggest that latanoprost monotherapy and timolol/dorzolamide combined therapy is equally effective in controlling IOP in patients with POAG.

20.
PAFMJ-Pakistan Armed Forces Medical Journal. 2012; 62 (2): 237-240
in English | IMEMR | ID: emr-133845

ABSTRACT

To determine the prevalence of trachoma and its potential risk factors in medical camps established by Pak Field Hospital in Darfur, Sudan. Cross sectional descriptive study. Pak Fd Hospital [Level III] free medical camps in Nyala city, Darfur, Sudan from August 2009 to December 2009. Out of 4326 patients reporting in medical camps, those with ocular symptoms/signs were evaluated for specific clinical signs of trachoma in accordance with WHO Trachoma Grading System. A comprehensive trachoma assessment proforma including patient demographic data, grading of trachoma signs and questionnaire about potential trachoma risk factors was completed for each eligible patient. Median age of the study population was 22 years [interquartile range 10-44 yrs]. There were 43% males and 57% females with median household size 7 [interquartile range 5-8] persons. Overall prevalence of trachoma was 8.73% [378/4326] with 268 [70.9%] patients having active trachoma and 110 [29.1%] having cicatricial trachoma. The prevelance of active trachoma was much higher in younger population while cicatricial trachoma was more common in older age group. Prevalence of potentially blinding trachoma in developing countries poses an arduous challenge for the healthcare authorities. Implementation of WHO recommended 'SAFE' strategy over the last decade has been successful in reducing the burden of trachoma in these countries

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